Analysis of animal models of ulcerative colitis based on characteristics of clinical symptoms of traditional Chinese and Wes-tern medicine / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 757-761, 2021.
Artículo
en Chino
| WPRIM
| ID: wpr-878936
ABSTRACT
This article aims to provide a good experimental method for the study of drug treatment of ulcerative colitis. According to the characteristics of ulcerative colitis's clinical symptoms, common ulcerative colitis animal models were analyzed. Based on the characteristics of clinical symptoms of traditional Chinese medicine and Western medicine for ulcerative colitis disease, the existing commonly used animal models of ulcerative colitis were analyzed to summarize the current matching degree, advantages and disadvantages of the exi-sting animal models of ulcerative colitis and clinical symptoms. At present, studies on ulcerative colitis mainly adopt four types of induction modeling methods, such as immunization, chemical stimulation, compound method and gene model. There are many reported methods of colitis modeling, but no model can reflect the characteristics of clinical symptoms of ulcerative colitis treated with Western or Chinese medicine. This article summarizes the characteristics, clinically relevant symptoms and applicable scope of immunization, chemical stimulation, compound method, and gene model, so as to provide a reliable animal model for subsequent studies of prevention and treatment of colitis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Colitis Ulcerosa
/
China
/
Charadriiformes
/
Modelos Animales de Enfermedad
/
Medicina
/
Medicina Tradicional China
Tipo de estudio:
Estudio diagnóstico
/
Estudio pronóstico
Límite:
Animales
País/Región como asunto:
Asia
Idioma:
Chino
Revista:
China Journal of Chinese Materia Medica
Año:
2021
Tipo del documento:
Artículo
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