Research progress on the relationship between the Raf murine sarcoma viral oncogene homolog B gene mutation and lymph node metastasis of papillary thyroid carcinoma / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 191-195, 2021.
Artículo
en Chino
| WPRIM
| ID: wpr-879266
ABSTRACT
In recent years, with the improvement of the sensitivity of examination equipment and the change of people's living environment and diet, the rate of thyroid cancer has risen rapidly, which has increased nearly five folds in 10 years. The pathogenesis, clinical manifestation, biological behavior, treatment and prognosis of thyroid carcinoma of different pathological types are obviously different. Papillary thyroid carcinoma (PTC) can develop at any age, which accounts for about 90% of thyroid cancer. It progresses slowly and has favourable prognosis, but lymph node metastasis appears easily. Whether PTC is accompanied by lymph node metastasis has an important impact on its prognosis and outcome. The Raf murine sarcoma viral oncogene homolog B(BRAF)gene mutation plays a crucial role in PTC lymph node metastasis. Having an in-depth understanding of the specific role and mechanism of BRAF gene mutation in PTC is expected to provide new ideas for diagnosis and treatment of PTC.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Oncogenes
/
Neoplasias de la Tiroides
/
Carcinoma Papilar
/
Proteínas Proto-Oncogénicas B-raf
/
Cáncer Papilar Tiroideo
/
Metástasis Linfática
/
Mutación
Límite:
Animales
/
Humanos
Idioma:
Chino
Revista:
Journal of Biomedical Engineering
Año:
2021
Tipo del documento:
Artículo
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