Two cases of tsutsugamushi disease complicated with splenic infarction / 대한내과학회지

ABSTRACT

Tsutsugamushi disease is an acute febrile illness caused by infection with Orientia tsutsugamushi transmitted by the bite of larval trombiculid mites and characterized by fever, myalgia, lymphadenopathy, rash and eschar. O. tsutsugamushi has been known to cause diffuse vasculitis of small blood vessels. Disseminated intravascular coagulation associated with endothelial cellular injury by O. tsutsugamushi has been occasionally reported. However, in our knowledge, splenic infarction-associated scrub typhus has not been previously reported. We experienced two cases of tsutsugamushi disease with splenic infarction, which were improved after doxycycline treatment finished.