A Case of Disseminated Candidiasis in a Patient with Toxic Epidermal Necrolysis / 감염

ABSTRACT

Candida species are pervasive pathogens capable of causing both local and systemic infections in hospitalized patients. Hematogenously disseminated candidiasis is a life-threatening infection that is associated with high mortality because of nonspecific symptoms and low culture positivity. Nosocomial disseminated candidiasis has increased during the last decade. Although several advances in the diagnosis and treatment of this serious infection have been made in recent years, early diagnosis has been difficult until now. We experienced a case of disseminated candidiasis, which developed during treatment of toxic epidermal necrolysis with steroid and antibiotics. The patient manifested with endopthalmitis, multiple pulmonary nodular infiltrates and spondylodiscitis. Disseminated candidiasis was confirmed by transbronchial lung biopsy and treated with amphotericin B.