Research progress in building and applying cardiomyocytes injury model / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1223-1227, 2020.
Artículo
en Inglés
| WPRIM
| ID: wpr-880589
ABSTRACT
Cardiomyocytes injury model has been widely used in the study for the molecular mechanism of cardiovascular diseases and drug action. It is very important to select the appropriate model due to the different formation mechanisms for various models. Clinical cardiovascular pathological change is relatively complex. Currently used models according to the characteristics of clinical cardiovascular diseases mainly include hydrogen peroxide-induced myocardial cell damage model, hypoxia reoxygenation injury model, adriamycin-induced myocardial cell damage model, high sugar high fat-induced myocardial cell damage model, and isoprenaline-induced myocardial cell damage model. Every model has its advantages as well as its disadvantages. The suitable model of myocardial cell injury can be selected according to the research purpose.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Investigación
/
Daño por Reperfusión Miocárdica
/
Hipoxia de la Célula
/
Ratas Sprague-Dawley
/
Miocitos Cardíacos
/
Miocardio
Tipo de estudio:
Estudio pronóstico
Límite:
Animales
Idioma:
Inglés
Revista:
Journal of Central South University(Medical Sciences)
Año:
2020
Tipo del documento:
Artículo
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