Research advances in add-on treatment for negative symptoms and cognitive dysfunction in schizophrenia / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1457-1463, 2020.
Artículo
en Inglés
| WPRIM
| ID: wpr-880607
ABSTRACT
Antipsychotic medication is the primary treatment for schizophrenia, which is effective on ameliorating positive symptoms and can reduce the risk of recurrence, but it has limited efficacy for negative symptoms and cognitive dysfunction. The negative symptoms and cognitive dysfunction seriously affects the life quality and social function for the patients with schizophrenia. Currently, there is plenty evidence that antipsychotic drugs combined with adjuvant therapy drugs can effectively improve the negative symptoms and cognitive dysfunction. These drugs include anti-oxidants, nicotinic acetylcholine receptors and neuro-inflammatory drugs (anti-inflammatory drugs, minocycline), which show potential clinical effects.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Esquizofrenia
/
Antipsicóticos
/
Disfunción Cognitiva
/
Antiinflamatorios
/
Minociclina
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Journal of Central South University(Medical Sciences)
Año:
2020
Tipo del documento:
Artículo
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