Chronic myeloid leukemia with a significant increase of monocytes and rare karyotype: A case report and literature review / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 322-327, 2021.
Artículo
en Inglés
| WPRIM
| ID: wpr-880662
ABSTRACT
Chronic myeloid leukemia with a significant increase of monocytes is rare and difficult to identify from chronic myelo-monocytic leukemia in clinic. A 31-year-old male patient with systemic pain was initially diagnosed as chronic myelo-monocytic leukemia, who was finally diagnosed as chronic myeloid leukemia by fusion gene and chromosome examination. In addition to the typical Ph chromosome, a rare chromosome translocation t(2; 7)(p13; p22) was observed. The detection of monocyte subsets by multi-parameter flow cytometry is a diagnostic marker to distinguish the above 2 diseases. The relationship between fusion genes and mononucleosis is not clear. Tyrosine kinase inhibitors or allogeneic hematopoietic stem cell transplantation can be used in the treatment for this disease.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Translocación Genética
/
Monocitos
/
Leucemia Mielógena Crónica BCR-ABL Positiva
/
Cariotipo
/
Cariotipificación
Límite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Journal of Central South University(Medical Sciences)
Año:
2021
Tipo del documento:
Artículo
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