MRN complex is an essential effector of DNA damage repair / 浙江大学学报（英文版）（B辑：生物医学和生物技术）

ABSTRACT

Genome stability can be threatened by both endogenous and exogenous agents. Organisms have evolved numerous mechanisms to repair DNA damage, including homologous recombination (HR) and non-homologous end joining (NHEJ). Among the factors associated with DNA repair, the MRE11-RAD50-NBS1 (MRN) complex (MRE11-RAD50-XRS2 in