Macrophage-derived small extracellular vesicles promote biomimetic mineralized collagen-mediated endogenous bone regeneration / 国际口腔科学杂志·英文版
International Journal of Oral Science
;
(4): 33-33, 2020.
Artículo
en Inglés
| WPRIM
| ID: wpr-880849
ABSTRACT
Macrophages play an important role in material-related immune responses and bone formation, but the functionality of macrophage-derived extracellular vesicles (EVs) in material-mediated bone regeneration is still unclear. Here, we evaluated intracellular communication through small extracellular vesicles (sEVs) and its effects on endogenous bone regeneration mediated by biomimetic intrafibrillarly mineralized collagen (IMC). After implantation in the bone defect area, IMC generated more neobone and recruited more mesenchymal stem cells (MSCs) than did extrafibrillarly mineralized collagen (EMC). More CD63
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Osteogénesis
/
Regeneración Ósea
/
Diferenciación Celular
/
Colágeno
/
Biomimética
/
Vesículas Extracelulares
/
Macrófagos
Idioma:
Inglés
Revista:
International Journal of Oral Science
Año:
2020
Tipo del documento:
Artículo
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