Diabetes fuels periodontal lesions via GLUT1-driven macrophage inflammaging / 国际口腔科学杂志·英文版
International Journal of Oral Science
;
(4): 11-11, 2021.
Artículo
en Inglés
| WPRIM
| ID: wpr-880865
ABSTRACT
Hyperglycemia induces chronic low-grade inflammation (inflammaging), which is a newly identified contributor to diabetes-related tissue lesions, including the inflammatory bone loss in periodontitis. It is also a secondary senescent pattern mediated by an increased burden of senescent cells and senescence-associated secretory phenotype (SASP). Macrophage is a key SASP-spreading cell and may contribute to the maintenance of SASP response in the periodontal microenvironment. Using a transgenic diabetic model (BLKS/J-Lepr
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Senescencia Celular
/
Diabetes Mellitus Experimental
/
Transportador de Glucosa de Tipo 1
/
Inflamación
/
Macrófagos
Límite:
Animales
Idioma:
Inglés
Revista:
International Journal of Oral Science
Año:
2021
Tipo del documento:
Artículo
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