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Roles of circular RNAs in ischemic stroke / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases ; (12): 126-131, 2021.
Artículo en Chino | WPRIM | ID: wpr-882379
ABSTRACT
Circular RNAs (circRNAs) are a type of endogenous non-coding RNAs discovered recently, which are produced by models such as circularization driven by intron pairing and are regulated by related regulatory factors. An important biological function of circRNAs is to act as a molecular sponge to make the level of microRNAs significantly change in a short period of time. A number of studies have shown that circRNAs are closely associated with ischemic stroke. Therefore, a better understanding of the function of circRNAs and its regulatory mechanism will help to explore the expression of circRNAs in early ischemic stroke and its molecular mechanism in the occurrence and development of ischemic stroke, so as to establish an early warning model to realize the early detection, early diagnosis and early treatment of ischemic stroke. This article reviews the definition, biological characteristics, and expression changes and roles of circRNAs after ischemic stroke.
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio pronóstico / Estudio de tamizaje Idioma: Chino Revista: International Journal of Cerebrovascular Diseases Año: 2021 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio pronóstico / Estudio de tamizaje Idioma: Chino Revista: International Journal of Cerebrovascular Diseases Año: 2021 Tipo del documento: Artículo