Application of probiotics intestinal preparation combined with early enteral nutrition in perioperative period of laparoscopic rectal cancer radical proctectomy / 中国医师进修杂志

ABSTRACT

Objective:To study the safety and practicability of probiotics intestinal preparation combined with early enteral nutrition in perioperative period of laparoscopic rectal cancer radical proctectomy.Methods:The clinical data of 131 patients who underwent selective laparoscopic rectal cancer radical proctectomy in Shengjing Hospital of China Medical University from January to June 2018 were retrospectively analyzed. Among them, 80 patients received probiotics intestinal preparation combined with early enteral nutrition (experimental group), and 51 patients received traditional intestinal preparation and postoperative treatment (control group). The bleeding volume during operation, hospitalization expenses, first exhaust time, postoperative hospitalization time, indwelling catheter time and complications were compared between 2 groups.Results:The bleeding volume during operation, hospitalization expenses, postoperative hospitalization time in experimental group were significantly less than those in control group (166.33 ± 15.18) ml vs. (226.47 ± 16.46) ml, (42 365 ± 3 921) yuan vs. (51 048 ± 4 772) yuan and (13.32 ± 1.03) d vs. (13.98 ± 1.29) d, and there were statistical differences ( P<0.01). There were no statistical difference in the first exhaust time, indwelling catheter time and incidence of complications between 2 groups ( P>0.05). Conclusions:The probiotics intestinal preparation combined with early enteral nutrition in perioperative period can reduce the hospitalization expenses and shorten the hospitalization time in patients undergoing laparoscopic rectal cancer radical proctectomy, which is safe and feasible.