High risk factors of stent occlusion in patients with acute iliofemoral vein thrombosis and Cockett syndrome / 中华普通外科杂志

ABSTRACT

Objective:To evaluatte the high risk factors of stent occlusion in patients with acute iliofemoral vein thrombosis and Cockett syndrome.Methods:The clinical data of 178 patients of Cockett syndrome and acute lower extremity deep vein thrombosis from Jan 2014 to Dec 2016 was analyzed retrospectively. All patients underwent catheter directed thrombolysis or percutaneous mechanical thrombectomy combined with stent placement. The patency rate of stent was followed up by color Doppler ultrasound. Patients were divided into study group (stent occlusion) and control group (stent patency).Results:The stent patency rate at 6 months was 83.7%, body mass index ( OR=1.245, 95% CI 1.097-1.413), time of thrombosis more than 2 weeks ( OR=3.899, 95% CI 1.147-13.257), low thrombus clearance ( OR=0.238, 95% CI 0.117-0.486) was the high risk factor of short-term stent occlusion. Stent patency rate at 3 years was 75.3%, body mass index( OR=1.225, 95% CI 1.076-1.394), thrombosis history more than 2 weeks( OR=11.777, 95% CI 2.576-53.832), malignant tumor( OR=4.444, 95% CI 1.153-17.127) , compression therapy( OR=0.332, 95% CI 0.113-0.977), low thrombus clearance( OR=0.184, 95% CI 0.089-0.381), long stents( OR=8.427, 95% CI 2.329-30.488) was the high risk factor for mid-term stent occlusion. Conclusions:Obesity, the duration of thrombus longer than 2 weeks and low thrombus clearance are the high risk factors of early stent occlusion, while malignant tumor, irregular compression therapy and long stents may lead to lower medium and long term patency rate of the stent.