Neuroimaging diagnosis of cerebral small vessel disease / 中华神经科杂志

ABSTRACT

The clinical diagnosis of cerebral small vessel disease (CSVD) is largely dependent on neuroimaging. Features seen on neuroimaging of CSVD include white matter hyperintensities, lacunes and lacunar stroke, microbleeds, and perivascular spaces, suggesting brain tissue injury secondary to microvascular changes. Additionally, with the rapid development of neuroimaging method, several new methods from magnetic resonance imaging (MRI), functional MRI and positron emission computed tomography are applied in the clinical diagnosis of CSVD. Therefore, unified understanding of terminology and de?nitions for imaging features of CSVD, and of protocols for image acquisition and assessment, makes a significant meaning in clinical diagnosis and research of CSVD.