Complex structures and diverse functions of nuclear bodies: a review / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 2223-2231, 2021.
Artículo
en Chino
| WPRIM
| ID: wpr-887791
ABSTRACT
Nuclear bodies are membrane-free nuclear substructures that are localized in the mammalian nuclear matrix region. They are multiprotein complexes that recruit other proteins to participate in various cellular activities, such as transcription, RNA splicing, epigenetic regulation, tumorigenesis and antiviral defense. It is of great significance to clarify the functions and regulatory mechanisms of nuclear bodies to probe related diseases and virus-host interactions. This review takes several nuclear bodies associated proteins as examples, summarizes the formation process, structure and functions of nuclear bodies, and focuses on their important roles in antiviral infection. It is expected to provide new insight into host antiviral mechanisms.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Proteínas Nucleares
/
Núcleo Celular
/
Cuerpos de Inclusión Intranucleares
/
Epigénesis Genética
Límite:
Animales
Idioma:
Chino
Revista:
Chinese Journal of Biotechnology
Año:
2021
Tipo del documento:
Artículo
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