Germacranolide sesquiterpenes from Carpesium cernuum and their anti-leukemia activity / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 528-535, 2021.
Artículo
en Inglés
| WPRIM
| ID: wpr-888781
ABSTRACT
In this study, three new germacranolide sesquiterpenes (1-3), together with six related known analogues (4-9) were isolated from the whole plant of Carpesium cernuum. Their structures were established by a combination of extensive NMR spectroscopic analysis, HR-ESIMS data, and ECD calculations. The anti-leukemia activities of all compounds towards three cell lines (HEL, KG-1a, and K562) were evaluated in vitro. Compounds 1-3 exhibited moderate cytotoxicity with IC
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ensayos de Selección de Medicamentos Antitumorales
/
Asteraceae
/
Células K562
/
Sesquiterpenos de Germacrano
/
Fitoquímicos
/
Antineoplásicos Fitogénicos
Límite:
Humanos
Idioma:
Inglés
Revista:
Chinese Journal of Natural Medicines (English Ed.)
Año:
2021
Tipo del documento:
Artículo
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