Expression patterns of Rho-associated protein kinase signaling pathway-related genes in mouse submandibular glands
International Journal of Oral Biology
;
: 81-84, 2021.
Artículo
en Inglés
| WPRIM
| ID: wpr-890995
ABSTRACT
Salivary glands are exocrine glands that secrete saliva into the oral cavity, and secreted saliva plays essential roles in oral health. Therefore, maintaining the salivary glands in an intact state is required for proper production and secretion of saliva. To investigate a specific signaling pathway that might affect the maintenance of mouse submandibular gland (SMGs), RNA sequencing was performed. In SMGs, downregulated expression patterns of Rho-associated protein kinase (ROCK) signaling pathway-related genes, including Rhoa, Rhob, Rhoc, Rock1, and Rock2, were observed. Gene expression profiling analyses of these genes indicate that the ROCK signaling pathway is a potential signal for SMG maintenance.
Texto completo:
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Inglés
Revista:
International Journal of Oral Biology
Año:
2021
Tipo del documento:
Artículo
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