Medullary thyroid carcinoma: a 30-year experience at one institution in Korea
Annals of Surgical Treatment and Research
; : 278-287, 2016.
Article
en En
| WPRIM
| ID: wpr-89529
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE: The objective of this study was to review the clinical outcome and prognosis of patients with sporadic and hereditary medullary thyroid cancer (MTC) who were treated at a single tertiary hospital in Korea. METHODS: We retrospectively reviewed the case files of 85 patients treated from August 1982 to February 2012. RESULTS: In all, 65 patients (76.5%) had sporadic MTC and 20 patients (23.5%) had hereditary MTC. Patients in the sporadic group were older than in the hereditary group (P < 0.001). However, the hereditary group had more tumor multiplicity (P < 0.001) and bilaterality (P < 0.001). Neither survival rate was significantly different between the sporadic and hereditary groups (P = 0.775 and P = 0.866). By multivariate analysis, distant metastasis was a significant prognostic factor for overall and progression-free survival. CONCLUSION: In general, patients with MTC have favorable outcomes. Distant metastasis appears to be the strongest predictor of overall and progression-free survival.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Pronóstico
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Glándula Tiroides
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Neoplasias de la Tiroides
/
Análisis Multivariante
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Tasa de Supervivencia
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Estudios Retrospectivos
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Supervivencia sin Enfermedad
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Centros de Atención Terciaria
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Corea (Geográfico)
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Metástasis de la Neoplasia
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Annals of Surgical Treatment and Research
Año:
2016
Tipo del documento:
Article