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A Case of Leclercia adecarboxylata Isolated from Dialysate in a Patient with Continuous Ambulatory Peritoneal Dialysis / 대한임상미생물학회지
Korean Journal of Clinical Microbiology ; : 113-116, 1998.
Artículo en Coreano | WPRIM | ID: wpr-90480
ABSTRACT
A 60-year-old male with continuous ambulatory peritoneal dialysis was admitted because of abdominal discomfort and turbid dialysate. He had a history of chronic renal failure due to diabetic nephropathy. His WBC count of perpheral blood was 8,500/mm3 (neutrophil 92%), and that of dialysate was 1,400/mm3 (polymorphonuclear leukocyte 69%, lymphocyte 31%). Pure growth of Leclercia adecarboxylata was isolated from dialysate. The L. adecarboxylata isolate was susceptible to ampicillin, ampicillin/sulbactam, cephalothin, cefoperazone, cefoxitin, cefotaxime, ceftazidime, aztreonam, imipenem, gentamicin, tobramycin, amikacin, tetracycline, trimethoprim- sulfamethoxazole and ciprofloxacin. Cephalothin & amikacin were added into dialysate, and his clinical symptoms and turbidity of dialysate were resolved. L. adecarboxylata has been rarely isolated from clinical specimens. To our knowledge, this is the first report of L. adecarboxylata isolated from clinical specimen in Korea. On review of the world literature, we found only 7 cases of L. adecarboxylata infections. This microorganism has been isolated from lower extremity wounds and sputum as part of a mixed flora in 3 cases and 1 case, respectively, but it was the only microorganism isolated from cultures of blood in 3 cases. These 3 patients with bacteremia due to L. adecarboxylata had severe underlying diseases, and clinical symptoms were developed after invasive procedures. All of the L. adecarboxylata isolates from clinical specimens were susceptible to antimicrobial agents tested, and the responses to antibiotic therapy were excellent. It is difficult to identify this organism because its biochemical reactions are similar to those of Escherichia coli, therefore careful identification is required. And additional studies are necessary to determine the pathogenic potential and route of infection of this organism.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Esputo / Sulfametoxazol / Tetraciclina / Tobramicina / Heridas y Lesiones / Aztreonam / Amicacina / Gentamicinas / Linfocitos / Ciprofloxacina Tipo de estudio: Estudio pronóstico Límite: Humanos / Masculino País/Región como asunto: Asia Idioma: Coreano Revista: Korean Journal of Clinical Microbiology Año: 1998 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Esputo / Sulfametoxazol / Tetraciclina / Tobramicina / Heridas y Lesiones / Aztreonam / Amicacina / Gentamicinas / Linfocitos / Ciprofloxacina Tipo de estudio: Estudio pronóstico Límite: Humanos / Masculino País/Región como asunto: Asia Idioma: Coreano Revista: Korean Journal of Clinical Microbiology Año: 1998 Tipo del documento: Artículo