Relationship of 1233A/T Polymorphism of Proteasome Subunit α Type 6 Gene with Cerebral Infarction / 中国康复理论与实践
Chinese Journal of Rehabilitation Theory and Practice
;
(12): 966-970, 2019.
Artículo
en Chino
| WPRIM
| ID: wpr-905667
ABSTRACT
Objective:
To evaluate the relationship between 1233A/T polymorphism of proteasome subunit α type 6 (PSMA6) gene and cerebral infarction in Chinese Han population.Methods:
From January, 2012 to April, 2015, 211 cerebral infarction patients (case group) and 201 healthy controls (control group) were selected in the study. The single nucleotide polymorphism of 1233A/T of PSMA6 gene was identified by polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP), and genotypes and allele frequency distributions in two groups were analyzed.Results:
The frequencies of CC, CT+TT genetype and the C allele all revealed no significant difference between two groups (χ2 < 0.053, P > 0.05). After stratified by gender, the difference among all genetypes and C allele were still not significant between two groups in either male or female (χ2 < 2.735, P > 0.05).Conclusion:
The 1233A/T of PSMA6 gene might not be associated with cerebral infarction.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Rehabilitation Theory and Practice
Año:
2019
Tipo del documento:
Artículo
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