Advances on animal experimental study of mesenchymal stem cell extracellular vesicles in the treatment of bronchopulmonary dysplasia / 中华实用儿科临床杂志

ABSTRACT

Bronchopulmonary dysplasia (BPD) is a chronic lung disease that commonly occurs in preterm infants requiring mechanical ventilation and oxygen therapy.BPD usually has a poor long-term prognosis due to the lack of effective prevention and treatment method currently, which is one of the medical problems to be solved urgently.Many animal experiments indicated that mesenchymal stem cell extracellular vesicles (MSC-EVs) can replace mesenchymal stem cells as an effective treatment strategy for BPD, which has great application prospect.At present, the use of MSC-EVs has gradually deepened into the molecular mechanism and made new progress.In order to explore the value of MSC-EVs in the treatment of BPD, the recent advances on the mechanism of MSC-EVs in the treatment of BPD are investigated.