Effects of different concentrations of bilirubin on neonatal kidney / 中华实用儿科临床杂志

ABSTRACT

Hyperbilirubinemia is the most common clinical symptom in neonates that requires evaluation and treatment.It has been confirmed that free indirect bilirubin of high concentration have direct toxic effect on nerve tissue and impair its function, but its effect on extraneural organs or systems (such as kidney, heart, liver, intestine, lung, blood coagulation and immune function) is still controversial.This present study reviewed the previous relevant research in recent years to understand the effect of bilirubin of different concentrations on neonatal kidney.