Serum ferritin level and the influencing factors in premature infants / 中国新生儿科杂志

ABSTRACT

Objective:To study the levels of serum ferritin (SF) in preterm infants of different gestational ages and analyze the influencing factors.Method:From October 2018 to October 2020, preterm infants hospitalized in our hospital were included for prospective study. According to the gestational age, the infants were assigned into 3 groups 34~36 w group, 32~33 w group and <32 w group. The SF levels were compared among the groups and the influencing factors were analyzed.Result:A total of 919 preterm infants were included, including 481 in the 34~36 w group, 293 in the 32~33 w group and 145 in the <32 w group. The incidence of Cesarean section in the <32 w group was lower than the other two groups ( P<0.001). The incidence of twin birth in the 32~33 w group was higher than the other two groups ( P<0.05). No significant differences existed in gender among the three groups ( P>0.05). The serum SF levels in the 34~36 w group, 32~33 w group and <32 w group were (240.1±167.4), (216.2±137.0) and (204.4±112.8)μg/L, respectively. The serum SF levels in the 34~36 w group were higher than the other two groups ( P<0.05). No significant differences existed in serum SF levels between the 32~33 w group and the <32 w group ( P>0.05). Multiple　linear　regression　analysis　showed　that SF levels were lower in premature infants with small gestational age and Cesarean section delivery ( P<0.05). Conclusion:SF levels in premature infants with small gestational age and Cesarean section delivery are lower and more monitoring of SF are needed.