The clinical significance and detection methods of programmed death protein 1 and its ligand expression in non-small cell lung cancer / 中国基层医药

ABSTRACT

In recent years, programmed death protein 1 and its ligand (PD-1/PD-L1) pathway as the main research direction of tumor therapy has brought changes to the treatment of non-small cell lung cancer in some patients. The curative effects of anti-PD-L1 inhibitors are positively correlated with the expression of PD-L1 in tumor tissues. However, different techniques are required to detect the expression of PD-L1 after application of different PD-1/PD-L1 inhibitors. Therefore, how to detect the expression of PD-L1 in tumor tissues efficiently and accurately is particularly important. This review summarizes the clinical significance and detection methods of PD-L1 expression in non-small cell lung cancer.