Progress in molecular mechanism and clinical application of primordial follicle activation / 中国医师杂志
Journal of Chinese Physician
; (12): 1281-1285, 2021.
Article
en Zh
| WPRIM
| ID: wpr-909697
Biblioteca responsable:
WPRO
ABSTRACT
With the continuous elucidation of the molecular mechanism of primordial follicle activation, clinical in vitro activation (IVA) has gradually become a clinical treatment for premature ovarian insufficiency (POI) and reduced ovarian reserve (DOR). This article will review the mechanism of phosphatase and tensin homolog (PTEN)/phosphatidylinositol-3-kinase (PI3K), hippo signal and mammalian target of rapamycin complex 1 (mTORC1) signal involved in the activation of primordial follicles, and the application of IVA in patients with POI and DOR.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Chinese Physician
Año:
2021
Tipo del documento:
Article