The progress on the mechanism of NLRP3 inflammasome in renal ischemia-reperfusion injury / 中华泌尿外科杂志
Chinese Journal of Urology
;
(12): 554-558, 2021.
Artículo
en Chino
| WPRIM
| ID: wpr-911071
ABSTRACT
Renal ischemia-reperfusion injury often occurs during operations that need to block the blood supply of the kidneys. It is an important pathophysiological process that affects the recovery of kidney function and causes acute renal failure. Activated NLRP3 inflammasome can mediate the maturation and release of a variety of pro-inflammatory factors, and participate in the inflammatory response in renal ischemia-reperfusion injury, thereby regulating body inflammation and related cell functions. This article summarized how NLRP3 inflammasome mediated the occurrence of inflammation in renal ischemia reperfusion injury, and further provied a new basis for the prevention and treatment of renal ischemia-reperfusion injury.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Urology
Año:
2021
Tipo del documento:
Artículo
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