Obesity-Related Digestive Diseases and Their Pathophysiology
Gut and Liver
;
: 323-334, 2017.
Artículo
en Inglés
| WPRIM
| ID: wpr-91130
ABSTRACT
Obesity is a growing medical and public health problem worldwide. Many digestive diseases are related to obesity. In this article, the current state of our knowledge of obesity-related digestive diseases, their pathogenesis, and the medical and metabolic consequences of weight reduction are discussed. Obesity-related digestive diseases include gastroesophageal reflux disease, Barrett’s esophagus, esophageal cancer, colon polyp and cancer, nonalcoholic fatty liver disease, hepatitis C-related disease, hepatocellular carcinoma, gallstone, cholangiocarcinoma, and pancreatic cancer. Although obesity-related esophageal diseases are associated with altered mechanical and humoral factors, other obesity-related digestive diseases seem to be associated with obesity-induced altered circulating levels of adipocytokines and insulin resistance. The relationship between functional gastrointestinal disease and obesity has been debated. This review provides a comprehensive evaluation of the obesity-related digestive diseases, including pathophysiology, obesity-related risk, and medical and metabolic effects of weight reduction in obese subjects.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Neoplasias Pancreáticas
/
Pólipos
/
Resistencia a la Insulina
/
Neoplasias Esofágicas
/
Pérdida de Peso
/
Reflujo Gastroesofágico
/
Cálculos Biliares
/
Salud Pública
/
Citocinas
/
Colon
Idioma:
Inglés
Revista:
Gut and Liver
Año:
2017
Tipo del documento:
Artículo
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