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Research progress of single nucleotide polymorphisms of risk gene of restless legs syndrome / 中华神经科杂志
Chinese Journal of Neurology ; (12): 1187-1193, 2021.
Artículo en Chino | WPRIM | ID: wpr-911855
ABSTRACT
Restless legs syndrome (RLS) is a kind of common diseases of the nervous system, of which adult prevalence rate is from 1% to 15%. The etiology, pathogenesis and related gene therapy of RLS are not fully understood. Studies have shown that RLS may be associated with the polymorphism of some risk genes. Genome-wide association studies have revealed a total of seven risk sites to date, including MEIS1, BTBD9, MAP2K5/SKOR1, PTPRD, TOX3, NOS1 and 2p14 intergenic regions. This article reviewed the research progress of single nucleotide polymorphisms in RLS risk genes in recent years.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio de etiología Idioma: Chino Revista: Chinese Journal of Neurology Año: 2021 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio de etiología Idioma: Chino Revista: Chinese Journal of Neurology Año: 2021 Tipo del documento: Artículo