A case of toxic epidermal necrolysis due to topiramate
Allergy, Asthma & Respiratory Disease
; : 102-104, 2020.
Article
en Ko
| WPRIM
| ID: wpr-913264
Biblioteca responsable:
WPRO
ABSTRACT
Topiramate is an antiepileptic drug effective for multiple types of seizure and is also used to prevent migraine attack. Several side effects have been reported, such as metabolic acidosis, nephrolithiasis, anorexia, weight reduction, drowsiness, glaucoma, hyperthermia, and cognitive dysfunction, whereas skin manifestationis were rarely reported. We report a case of a 12-year-old girl on medication of topiramate for 8 months due to focal epilepsy. She had fever, sore throat, burning sense in the vaginal area, and then flaccid bullae and erythematous patches proceeded to the whole bodyskin and mucosa including the conjunctiva, oral cavity, and genital areas. She was diagnosed with toxic epidermal necrolysis (TEN) and improved after the discontinuation of topiramate and with administration of high-dose intravenous steroid and immunoglobulin. We, herein, report a girl who developed severe side effects on the skin, TEN, due to topiramate.
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Índice:
WPRIM
Idioma:
Ko
Revista:
Allergy, Asthma & Respiratory Disease
Año:
2020
Tipo del documento:
Article