The role of nuclear factor I-C in tooth and bone development
Journal of the Korean Association of Oral and Maxillofacial Surgeons
; : 63-69, 2017.
Article
en En
| WPRIM
| ID: wpr-91687
Biblioteca responsable:
WPRO
ABSTRACT
Nuclear factor I-C (NFI-C) plays a pivotal role in various cellular processes such as odontoblast and osteoblast differentiation. Nfic-deficient mice showed abnormal tooth and bone formation. The transplantation of Nfic-expressing mouse bone marrow stromal cells rescued the impaired bone formation in Nfic(-/-) mice. Studies suggest that NFI-C regulate osteogenesis and dentinogenesis in concert with several factors including transforming growth factor-β1, Krüppel-like factor 4, and β-catenin. This review will focus on the function of NFI-C during tooth and bone formation and on the relevant pathways that involve NFI-C.
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Texto completo:
1
Índice:
WPRIM
Asunto principal:
Osteoblastos
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Osteogénesis
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Osteoporosis
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Diente
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Desarrollo Óseo
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Dentinogénesis
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Factores de Transcripción NFI
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Células Madre Mesenquimatosas
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Odontoblastos
Límite:
Animals
Idioma:
En
Revista:
Journal of the Korean Association of Oral and Maxillofacial Surgeons
Año:
2017
Tipo del documento:
Article