Seroprevalence to Coxiella burnetii in Patients with Acute Febrile Episodes during 1993
Journal of Bacteriology and Virology
;
: 299-306, 2002.
Artículo
en Coreano
| WPRIM
| ID: wpr-91831
ABSTRACT
Coxiella burnetii is the etiological agent of Q fever, that may occur either acutely or the chronically. To understand the seroepidemiological patterns of C. burnetii infection in Korea, we examined a total of 3,178 sera from patients with acute febrile episodes by using indirect immunofluorescence assay (IFA) for detectable antibodies to C. burnetii and other eight rickettsial antigens. The IFA seropositivity>or=120 for C. burnetii phase II was 11.5% (368 out of 3,178 sera). The co-existence of antibodies to other rickettsial antigens was found in 216 out of the 368 positive sera. Thirty-seven point five percent (n=138) had antibodies to R. tsutsugamushi (cutoff>or=120), 16% (n=59) to Ehrlichia sennetsu, 14.9% (n=55) to Rickettsia typhi, 13.5% (n=50) to R. akari, 11.4% (n=42) to R. japonica, 8.9% (n=33) to R. prowazekii, 7.6% (n=28) to R. sibirica, and 6.7% (n=25) to R. conorii by IFA, respectively. These results are consistent with previous reports documenting diverse serum cross-reactivity in chronic Q fever. Therefore we excluded the samples that reacted to other rickettsial antigens at same or higher titers than to C. burnetii, resulting in the seropositive rate of 4.1%. The serological prevalence was 2% (n=64) when the conventional cut-off titer of 180 was used. Our results suggest that infections with C. burnetii are more prevalent than expected previously and should be differentially diagnosised for febrile illness occurring after exposure to ticks or other vectors.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fiebre Q
/
Rickettsia
/
Rickettsia typhi
/
Garrapatas
/
Estudios Seroepidemiológicos
/
Prevalencia
/
Coxiella burnetii
/
Técnica del Anticuerpo Fluorescente Indirecta
/
Coxiella
/
Neorickettsia sennetsu
Tipo de estudio:
Estudio diagnóstico
/
Estudio de prevalencia
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Coreano
Revista:
Journal of Bacteriology and Virology
Año:
2002
Tipo del documento:
Artículo
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