Logopenic Progressive Aphasia Revealing Positive Cerebrospinal Fluid Biomarkers for Alzheimer's Disease
Journal of the Korean Neurological Association
;
: 98-102, 2014.
Artículo
en Coreano
| WPRIM
| ID: wpr-91986
ABSTRACT
Primary progressive aphasia (PPA) is classified into agrammatic, semantic, and logopenic variants, but differential diagnosis is often challenging. There is accumulating evidence that the neuropathology of logopenic PPA is distinct from that of the other types. We report herein a woman with logopenic PPA who was diagnosed by clinical, neuropsychological, and radiologic data during 2 years of follow-up. Interestingly, her cerebrospinal fluid biomarkers were found to be similar to those found in Alzheimer's disease, with a decreased concentration of Abeta42 and an increased concentration of pTau181 (tTau).
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Afasia
/
Semántica
/
Biomarcadores
/
Líquido Cefalorraquídeo
/
Estudios de Seguimiento
/
Afasia Progresiva Primaria
/
Diagnóstico Diferencial
/
Enfermedad de Alzheimer
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
Límite:
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Neurological Association
Año:
2014
Tipo del documento:
Artículo
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