Exosomal microRNAs: an emerging player in systemic lupus erythematosus / 生理学报
Acta Physiologica Sinica
;
(6): 1035-1042, 2021.
Artículo
en Chino
| WPRIM
| ID: wpr-921308
ABSTRACT
Exosomes are nanometer-sized membranous extracellular vesicles that can be secreted by almost all types of cells in the body. Exosomes are involved in cell-to-cell communication through autocrine and paracrine forms. Exosomal microRNAs (miRNAs) are stable in plasma, urine and other body fluids, and have various biological functions. They play an irreplaceable role in the occurrence, development, immune regulation of systemic lupus erythematosus (SLE). Recent studies have proposed that exosomal miRNAs have promising application prospects in the pathogenesis, early diagnosis, and treatment of SLE. Therefore, this review aims to introduce the current research progress on exosomal miRNAs in SLE and analyze their potential application value.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Comunicación Celular
/
MicroARNs
/
Exosomas
/
Lupus Eritematoso Sistémico
Tipo de estudio:
Estudio de tamizaje
Límite:
Humanos
Idioma:
Chino
Revista:
Acta Physiologica Sinica
Año:
2021
Tipo del documento:
Artículo
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