Research progress of respiratory syncytial virus (RSV) infection and respiratory diseases in infancy / 生理学报
Acta Physiologica Sinica
;
(6): 1043-1053, 2021.
Artículo
en Chino
| WPRIM
| ID: wpr-921309
ABSTRACT
Lower respiratory tract infection (LRTI) induced by respiratory syncytial virus (RSV) is an important cause of hospitalization for infants. Compared with adults, infants are more likely to cause serious respiratory diseases after RSV infection due to the specific immature airway structure and immune system. The balance of immune resistance and immune tolerance of the host is critical to effective virus clearance and disease control. This paper reviews the relationship between RSV infection and respiratory diseases in infancy, the influence factors of the high pathogenicity of RSV infection in early life, as well as the research progress of anti-RSV therapy, and expands the specific molecular events regulating immune resistance and immune tolerance. We expect to present new ideas for the prevention and treatment of RSV-related respiratory diseases in clinical practice.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Trastornos Respiratorios
/
Virus Sincitiales Respiratorios
/
Infecciones del Sistema Respiratorio
/
Infecciones por Virus Sincitial Respiratorio
Límite:
Humanos
/
Lactante
Idioma:
Chino
Revista:
Acta Physiologica Sinica
Año:
2021
Tipo del documento:
Artículo
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