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Local administration of parathyroid hormone and parathyroid hormone-related peptides for bone tissue engineering / 生物医学工程学杂志
Journal of Biomedical Engineering ; (6): 1028-1034, 2021.
Artículo en Chino | WPRIM | ID: wpr-921842
ABSTRACT
Parathyroid hormone (PTH) exerts multiple effects such as regulating bone remodeling, promoting angiogenesis, etc., and it is an active factor with great application potential for bone repair. In recent years, with the development of scaffold material loading strategies and parathyroid hormone-related peptides (PTHrPs), in situ loading of PTH or PTHrPs on scaffold materials to promote bone defect healing gradually becomes possible. Based on the current status and challenges of intermittent PTH (iPTH) for bone tissue engineering, the review summarizes the in-situ application strategies of PTH and the construction of PTHrPs as well as current problems and further directions in this field, with a view to propel the clinical application of scaffold materials loaded with PTH or PTHrPs
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Hormona Paratiroidea / Cicatrización de Heridas / Huesos / Ingeniería de Tejidos / Andamios del Tejido Idioma: Chino Revista: Journal of Biomedical Engineering Año: 2021 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Hormona Paratiroidea / Cicatrización de Heridas / Huesos / Ingeniería de Tejidos / Andamios del Tejido Idioma: Chino Revista: Journal of Biomedical Engineering Año: 2021 Tipo del documento: Artículo