Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts / 中国结合医学杂志
Chinese journal of integrative medicine
;
(12): 760-766, 2021.
Artículo
en Inglés
| WPRIM
| ID: wpr-922118
ABSTRACT
OBJECTIVE@#To investigate the molecular mechanisms underlying the effects of arsenic trioxide (As@*METHODS@#Transplantation of LVG hamster hearts to Lewis rats was performed by anastomosis of vessels in the neck using end-to-end anastomosis with a non-suture cuff technique. Four groups of recipient rats (n=6 in each) were treated with normal saline (control), As@*RESULTS@#Expression of Nrf2-ARE-HO-1 signaling pathway was upregulated in heart xenografts in rats treated with As@*CONCLUSION@#Combination treatment with As
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Ratas Endogámicas Lew
/
Transducción de Señal
/
Trasplante de Corazón
/
Hemo-Oxigenasa 1
/
Factor 2 Relacionado con NF-E2
/
Xenoinjertos
/
Trióxido de Arsénico
/
Leflunamida
Límite:
Animales
Idioma:
Inglés
Revista:
Chinese journal of integrative medicine
Año:
2021
Tipo del documento:
Artículo
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