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Role of the ES-62 protein derived from Acanthocheilonema viteae in regulation of immune dysregulation diseases: a review / 中国血吸虫病防治杂志
Article en Zh | WPRIM | ID: wpr-923786
Biblioteca responsable: WPRO
ABSTRACT
ES-62 is a phosphorylcholine-containing, 62 kDa glycoprotein derived from the excretory-secretory product of Acanthocheilonema viteae, which is effective for the prevention and treatment of immune dysregulation diseases through triggering activation of immune cells, such as dendritic cells, mononuclear macrophages and regulatory B cells and mediating immune responses. Recently, the role of the ES-62 protein in the management of allergic, autoimmune and metabolic diseases has been paid much attention. This review summarizes the regulatory role of the ES-62 protein in immune dysregulation diseases and the underlying mechanisms, so as to provide insights into future experimental studies.
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Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Chinese Journal of Schistosomiasis Control Año: 2021 Tipo del documento: Article
Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Chinese Journal of Schistosomiasis Control Año: 2021 Tipo del documento: Article