A Preliminary Study for the Effect of Coix-seed Reactive Derivatives (CRD) on Human Skin Fibroblast Proliferation and Collagen Production / 日本補完代替医療学会誌
Japanese Journal of Complementary and Alternative Medicine
;
: 61-64, 2022.
Artículo
en Japonés
| WPRIM
| ID: wpr-924396
ABSTRACT
Objective:
We investigated the effects of Coix-seed Reactive Derivatives (CRD) on fibroblast proliferation and collagen production.Methods:
Various concentrations of CRD (0.00001%, 0.0001%, 0.001%, 0.01%, 0.1%, 1%) were added to human fibroblasts, and changes in cell count and extracellular collagen production were measured.Results:
Fibroblasts proliferated by the addition of CRD, peaked at about 1.7 times when the CRD concentration was 0.0001%, and then decreased as the addition concentration increased. On the other hand, the collagen concentration in the extracellular matrix of fibroblasts increased as the CRD addition concentration increased, and the collagen concentration increased sharply at 0.1% of CRD concentration or more.Conclusion:
It was suggested that CRD has a function of increasing the proliferation of fibroblasts and collagen production.
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Japonés
Revista:
Japanese Journal of Complementary and Alternative Medicine
Año:
2022
Tipo del documento:
Artículo
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