From MAFLD to hepatocellular carcinoma and everything in between / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 547-556, 2022.
Artículo
en Inglés
| WPRIM
| ID: wpr-927546
ABSTRACT
Metabolic (dysfunction) associated fatty liver disease (MAFLD), previously known as non-alcoholic fatty liver disease, is the most common cause of chronic liver disease worldwide. Many risk factors contribute to the pathogenesis of MAFLD with metabolic dysregulation being the final arbiter of its development and progression. MAFLD poses a substantial economic burden to societies, which based on current trends is expected to increase over time. Numerous studies have addressed various aspects of MAFLD from its risk associations to its economic and social burden and clinical diagnosis and management, as well as the molecular mechanisms linking MAFLD to end-stage liver disease and hepatocellular carcinoma. This review summarizes current understanding of the pathogenesis of MAFLD and related diseases, particularly liver cancer. Potential therapeutic agents for MAFLD and diagnostic biomarkers are discussed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Factores de Riesgo
/
Carcinoma Hepatocelular
/
Enfermedad del Hígado Graso no Alcohólico
/
Neoplasias Hepáticas
Tipo de estudio:
Estudio de etiología
/
Factores de riesgo
Límite:
Humanos
Idioma:
Inglés
Revista:
Chinese Medical Journal
Año:
2022
Tipo del documento:
Artículo
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