Acute kidney injury and regulated cell death / 生理学报
Acta Physiologica Sinica
;
(6): 4-14, 2022.
Artículo
en Chino
| WPRIM
| ID: wpr-927576
ABSTRACT
Acute kidney injury (AKI) refers to a clinical syndrome in which renal function declines rapidly in a short period of time caused by various pathological factors. During the development of AKI, renal tubules with the functions of reabsorption and excretion are prone to cell death due to external pathological stimuli, which is an important cause of impaired renal function. In recent years, a variety of new cell death pathways have been gradually recognized. Researchers have now found that regulated cell death (RCD), such as necroptosis, pyroptosis and ferroptosis, are important regulatory mechanisms of AKI. This article will summarize the research advances of various types of RCD involved in the process of AKI, aiming to deepen the understanding of AKI and provide innovative thoughts for the clinical treatment of AKI.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Muerte Celular
/
Lesión Renal Aguda
/
Necroptosis
/
Muerte Celular Regulada
/
Riñón
/
Necrosis
Límite:
Humanos
Idioma:
Chino
Revista:
Acta Physiologica Sinica
Año:
2022
Tipo del documento:
Artículo
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