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Production of carboxylic acids by metabolically engineered Yarrowia lipolytica: a review / 生物工程学报
Chinese Journal of Biotechnology ; (12): 1360-1372, 2022.
Artículo en Chino | WPRIM | ID: wpr-927786
ABSTRACT
Yarrowia lipolytica is a non-conventional yeast with unique physiological and metabolic characteristics. It is suitable for production of various products due to its natural ability to utilize a variety of inexpensive carbon sources, excellent tolerance to low pH, and strong ability to secrete metabolites. Currently, Y. lipolytica has been demonstrated to produce a wide range of carboxylic acids with high efficiency. This article summarized the progress in engineering Y. lipolytica to produce various carboxylic acids by using metabolic engineering and synthetic biology approaches. The current bottlenecks and solutions for high-level production of carboxylic acids by engineered Y. lipolytica were also discussed, with the aim to provide useful information for relevant studies in this field.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Ácidos Carboxílicos / Yarrowia / Biología Sintética / Ingeniería Metabólica Idioma: Chino Revista: Chinese Journal of Biotechnology Año: 2022 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Ácidos Carboxílicos / Yarrowia / Biología Sintética / Ingeniería Metabólica Idioma: Chino Revista: Chinese Journal of Biotechnology Año: 2022 Tipo del documento: Artículo