Peutz-Jeghers Syndrome with Adenomatous Change in a Fifteen-month-old Boy / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 106-110, 2015.
Artículo
en Coreano
| WPRIM
| ID: wpr-92779
ABSTRACT
Peutz-Jeghers syndrome (PJS) is a very rare genetic disorder. PJS carries a high risk of developing gastrointestinal (GI) cancer or non-GI cancer with advancing years. However, major symptoms of PJS in childhood are obstruction, intussusception, and bleeding from hamartomatous intestinal polyps which in majority of cases are not related to cancer. Generally, first GI symptom develops by 20 years in one half of children diagnosed with PJS. Children under two years of age who had PJS polyp-related intestinal symptoms are rare, and there have been no published report on intestinal carcinoma development, adenomatous change or dysplasia of polyps in Korean children with PJS. Recently, the authors have experienced a case PJS with adenomatous polyp change in a 15-month-old boy who had STK11 gene mutation. Therefore, early evaluation could be necessary and considered in children with PJS.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pólipos
/
Síndrome de Peutz-Jeghers
/
Secuencia de Bases
/
Adenoma
/
Colonoscopía
/
Proteínas Serina-Treonina Quinasas
/
Polimorfismo de Nucleótido Simple
/
Heterocigoto
Límite:
Humanos
/
Lactante
/
Masculino
Idioma:
Coreano
Revista:
The Korean Journal of Gastroenterology
Año:
2015
Tipo del documento:
Artículo
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