Clinical value of metagenomic next-generation sequencing in complicated infectious diseases / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 210-215, 2022.
Artículo
en Inglés
| WPRIM
| ID: wpr-928589
ABSTRACT
Infectious diseases are commonly seen in clinical practice, and pathogen diagnosis is the key link in diagnosis and treatment; however, conventional pathogen detection methods cannot meet clinical needs due to time-consuming operation and low positive rate. As a new pathogen detection method, metagenomic next-generation sequencing (mNGS) has a wide detection range and can detect bacteria, viruses, fungi, parasites, rare pathogens, and even unknown pathogens. The technique of mNGS is unbiased and can rapidly, efficiently, and accurately obtain all nucleic acid information in test samples, analyze pathogens, and guide clinical diagnosis and treatment, thereby playing an important role in complicated infectious diseases. This article reviews the diagnostic advantages and clinical value of mNGS in bacterial, fungal, viral, and parasitic infections.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Bacterias
/
Enfermedades Transmisibles
/
Sensibilidad y Especificidad
/
Metagenómica
/
Secuenciación de Nucleótidos de Alto Rendimiento
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Chinese Journal of Contemporary Pediatrics
Año:
2022
Tipo del documento:
Artículo
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