Recent research on tofacitinib in the treatment of pediatric rheumatic diseases / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 447-453, 2022.
Artículo
en Chino
| WPRIM
| ID: wpr-928629
ABSTRACT
Tofacitinib is a Janus kinase inhibitor and can block the Janus kinase-signal transducer and activator of transcription signal transduction pathway and reduce the production and release of a variety of cytokines. It has great potential in the treatment of various rheumatic diseases with a rapid onset of action and can reduce corticosteroid dependence and related adverse events. The therapeutic effect of tofacitinib in adult patients has been confirmed, and it has been increasingly used in pediatric patients in recent years. This article reviews the clinical application of tofacitinib in the treatment of pediatric autoimmune diseases.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Piperidinas
/
Pirimidinas
/
Enfermedades Reumáticas
/
Inhibidores de Proteínas Quinasas
/
Quinasas Janus
Límite:
Adulto
/
Niño
/
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Contemporary Pediatrics
Año:
2022
Tipo del documento:
Artículo
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