Research Status of Tumor-associated Fibroblasts Regulating Immune Cells / 中国肺癌杂志
Chinese Journal of Lung Cancer
;
(12): 207-213, 2022.
Artículo
en Chino
| WPRIM
| ID: wpr-928799
ABSTRACT
Cancer-associated fibroblasts (CAFs) and tumor-infiltrating immune cells are the most essential components of the tumor microenvironment (TME). They communicate with each other in tumor microenvironment and play a critical role in tumorigenesis and development. CAFs are very heterogeneous and different subtypes of CAFs display different functions. At the same time, it can contribute to the regulation of the function of tumor-infiltrating immune cells and eventually result in the carcinogenesis, tumor progression, invasion, metastasis and other biological behaviors of tumors by producting various growth factors and cytokines etc. Based on the current research results at home and abroad, this paper reviews the recent research progress on the regulation of CAFs on infiltrating immune cells in tumor microenvironment.
.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Transformación Celular Neoplásica
/
Microambiente Tumoral
/
Carcinogénesis
/
Fibroblastos Asociados al Cáncer
/
Neoplasias Pulmonares
Límite:
Humanos
Idioma:
Chino
Revista:
Chinese Journal of Lung Cancer
Año:
2022
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS