Two cases of idiopathic membranous nephropathy treated with rituximab
Kidney Research and Clinical Practice
; : 138-141, 2013.
Article
en En
| WPRIM
| ID: wpr-92912
Biblioteca responsable:
WPRO
ABSTRACT
Idiopathic membranous nephropathy is a common cause of nephrotic syndrome, and has been reported as a cause of idiopathic primary glomerulonephropathy in up to 90% of patients. However, the treatment options remain controversial. We report two cases of idiopathic membranous nephropathy that were treated with rituximab. A 54-year-old man and a 64-year old man were admitted for rituximab therapy. They had previously been treated with combinations of immunosuppressive agents including cyclophosphamide, cyclosporine, mycophenolate, and steroids. However, the patients' heavy proteinuria was not resolved. Both patients received rituximab therapy, 2 weeks apart. After several months of follow-up and a second round of rituximab treatment for each patient, their proteinuria decreased and partial remission of disease was achieved in both patients.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Proteinuria
/
Esteroides
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Glomerulonefritis Membranosa
/
Estudios de Seguimiento
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Ciclosporina
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Ciclofosfamida
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Anticuerpos Monoclonales de Origen Murino
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Rituximab
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Inmunosupresores
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Síndrome Nefrótico
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Kidney Research and Clinical Practice
Año:
2013
Tipo del documento:
Article