Optimization of extraction technology of total saponins from Trillium tschonoskii Rhizome by response surface method / 国际中医中药杂志
International Journal of Traditional Chinese Medicine
; (6): 56-60, 2022.
Article
en Zh
| WPRIM
| ID: wpr-930099
Biblioteca responsable:
WPRO
ABSTRACT
Objective:To optimize the ethanol reflux extraction process of total saponins in total saponins of Trillium tschonoskii Rhizome. Methods:On the basis of single factor tests, making the total extraction rate of three main compounds [paris saponin Ⅵ, paris saponin Ⅶ and pennogenin-3- O-α-L-rhamnopyranosyl-(1→4)-[O-α-L-rhamnopyranosyl (1→2)]- O-β-D-glucopyranoside (PRRG)] as the indicator, the optimal extraction parameter was selected with the main influencing factors: the ethanol concentration, solid-liquid ratio, and extraction time by the central composite design-response surface method.Results:The optimal extraction parameter for the ethanol extract of total saponins of Trillium tschonoskii Rhizome was as follows: ethanol concentration 69%, extraction time 1.9 h, and solid liquid ratio 1∶9.7. The binomial fitting complex correlation coefficient r = 0.966 1, and the deviation between the extracted predicted value and the actual value is 4.68%. Conclusion:The central composite design-response surface method is simple and reliable for the optimization of extraction process of total saponins of Trillium tschonoskii Rhizome.
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WPRIM
Tipo de estudio:
Prognostic_studies
Idioma:
Zh
Revista:
International Journal of Traditional Chinese Medicine
Año:
2022
Tipo del documento:
Article