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Research progress of interleukin-1 and its receptor antagonist Anakinra in Kawasaki disease / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics ; (24): 233-237, 2022.
Artículo en Chino | WPRIM | ID: wpr-930411
ABSTRACT
Kawasaki disease (KD) is an acute vasculitis that often occurs in children under 5 years of age, leading to coronary artery aneurysms.It is the leading cause of acquired heart disease in children in many countries.Coronary artery stenosis, thrombosis, and even myocardial infarction may occur in the long-term course of KD, which seriously threaten the health of children.The etiology and pathogenesis of KD are complex, and it is recognized that KD is caused by the interaction of multiple factors like the heredity, immunity, inflammation, and environmental factors.Interleukin-1 plays an important role in the occurrence and progression of KD.This study mainly reviews the research progress of interleukin-1 and its receptor antagonist Anakinra in KD.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Applied Clinical Pediatrics Año: 2022 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Journal of Applied Clinical Pediatrics Año: 2022 Tipo del documento: Artículo