Research progress on naltrexone in the treatment of children with inflammatory bowel disease / 中国小儿急救医学

ABSTRACT

Inflammatory bowel disease refers to a group of non-specific chronic gastrointestinal inflammatory diseases of unknown causes, including ulcerative colitis, Crohn′s disease and indeterminate colitis.Recently, the incidence of inflammatory bowel disease in children has increased, which seriously affects the growth and development of children and the quality of life.Studies have shown that the opioid receptor antagonist naltrexone can reverse the inflammatory activity in inflammatory bowel disease and promote cell repair.This review summarized the research of application of naltrexone in the treatment of inflammatory bowel disease, aiming to further explore the effectiveness and safety of naltrexone in the treatment of inflammatory bowel disease in children.