Treatment of Psoriasis with Calcipotriol-PUVA / 대한피부과학회지
Korean Journal of Dermatology
;
: 772-776, 2000.
Artículo
en Coreano
| WPRIM
| ID: wpr-93217
ABSTRACT
BACKGROUND:
PUVA photochemotherapy has been accepted as an effective treatment modality in the treatment of psoriasis. Many combination therapies have been tried to reduce the long-term side effects of UV radiation.OBJECTIVE:
We performed conventional PUVA and calcipotriol-PUVA combination therapy to compare the effectiveness between two treatment modalities.METHODS:
We treated 38 Korean patients with conventional PUVA and 54 with D-PUVA. We compared the total number, duration and total UVA dose of PUVA therapy to reach grade 4 between two groups. We categorized each patient into clearing, improvement, or failure groups based on the therapeutic efficacy, and evaluated PASI score at patient`s visits.RESULTS:
The irradiation number and total cumulative dose of D-PUVA phototherapy to achieve grade 4 were significantly smaller than PUVA phototherapy.CONCLUSION:
Combining PUVA with a vitamin D analogue, calcipotriol, in the treatment of psoriasis may lead to lowering the risk of long-term exposure to UV radiation with higher efficacy.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fototerapia
/
Fotoquimioterapia
/
Psoriasis
/
Terapia PUVA
/
Vitamina D
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Año:
2000
Tipo del documento:
Artículo
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